DNMT3A IS DOWNREGULATED BY STAT5A AND MEDIATES G0/G1 ARREST BY SUPPRESSING THE MIR-17-5P/CDKN1A AXIS IN JAK2V617F CELLS

Dnmt3a is downregulated by Stat5a and mediates G0/G1 arrest by suppressing the miR-17-5p/Cdkn1a axis in Jak2V617F cells

Abstract Background Despite of the frequently reported Dnmt3a abormality in classical myeloproliferative neoplasms (cMPNs) patients, few research explores how the Dnmt3a is regulated by Jak2V617F mutation.In this study, we have investigated how the Dnmt3a is regulated by Jak2V617F mutation and its effects on downstream signaling pathways in cMPNs.M

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Image Creation about Africa Within the State-Owned Media Space: A Content Analysis of the Ghanaian Times Newspaper

This study attempted to find out the various images or themes that the Ghanaian Times as a State-owned Print Media in Ghana portrays about Africa through its reportage.Utilizing the Soundbar gatekeeping, cultural imperialist, and framing theories, the study looked at the selection of stories by the editors and the final images that were portrayed a

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